TY - GEN AU - Janetka,James W AU - Almeida,Lynsie AU - Ashwell,Susan AU - Brassil,Patrick J AU - Daly,Kevin AU - Deng,Chun AU - Gero,Thomas AU - Glynn,Roberta E AU - Horn,Candice L AU - Ioannidis,Stephanos AU - Lyne,Paul AU - Newcombe,Nicholas J AU - Oza,Vibha B AU - Pass,Martin AU - Springer,Stephanie K AU - Su,Mei AU - Toader,Dorin AU - Vasbinder,Melissa M AU - Yu,Dingwei AU - Yu,Yan AU - Zabludoff,Sonya D TI - Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors SN - 1464-3405 PY - 2008///1117 KW - Amides KW - chemistry KW - Apoptosis KW - Carbon KW - Cell Cycle KW - Checkpoint Kinase 1 KW - Chemistry, Pharmaceutical KW - methods KW - DNA Damage KW - Drug Design KW - Humans KW - Inhibitory Concentration 50 KW - Models, Chemical KW - Phenyl Ethers KW - Protein Kinase Inhibitors KW - chemical synthesis KW - Protein Kinases KW - Thiophenes KW - Urea N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2008.05.016 ER -