Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system. [electronic resource]
- Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jan 2009
- 424-35 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1740-634X
10.1038/npp.2008.73 doi
Animals Arcuate Nucleus of Hypothalamus--drug effects Blood Glucose--analysis Corticosterone--blood Dose-Response Relationship, Drug Eating--drug effects Hypothalamus--drug effects Male Melanocyte-Stimulating Hormones--pharmacology Mice Mice, Knockout Neurons--drug effects Neuropeptide Y--metabolism Peptide Fragments--pharmacology Pituitary Adenylate Cyclase-Activating Polypeptide--antagonists & inhibitors Pro-Opiomelanocortin--genetics RNA, Messenger--metabolism Receptor, Melanocortin, Type 3--antagonists & inhibitors Receptor, Melanocortin, Type 4--antagonists & inhibitors Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I--genetics Vasoactive Intestinal Peptide--pharmacology