Mazor, Ohad

Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase. [electronic resource] - Molecular pharmacology Sep 2008 - 755-63 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1521-0111

10.1124/mol.108.047449 doi


Acetylcholinesterase--pharmacokinetics
Alanine--genetics
Amino Acid Substitution
Animals
Binding Sites
Cell Line
Cholinesterase Inhibitors--pharmacology
Enzyme Activation--drug effects
Humans
Hydrolysis--drug effects
Kinetics
Male
Mice
Mice, Inbred ICR
Organophosphorus Compounds--metabolism
Phenylalanine--genetics
Phosphorylation--drug effects
Polyethylene Glycols--pharmacokinetics
Soman--toxicity
Survival Analysis
Time Factors