Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells. [electronic resource]
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Jul 2008
- 2358-64 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0278-6915
10.1016/j.fct.2008.03.016 doi
Antineoplastic Agents--pharmacology Carcinoma, Hepatocellular--drug therapy Dose-Response Relationship, Drug Down-Regulation Drug Screening Assays, Antitumor Humans Isothiocyanates--pharmacology Liver Neoplasms--drug therapy Matrix Metalloproteinase 2--metabolism Matrix Metalloproteinase 9--metabolism Matrix Metalloproteinase Inhibitors Metalloproteases--antagonists & inhibitors Mitogen-Activated Protein Kinases--antagonists & inhibitors Neoplasm Invasiveness Neoplasm Metastasis Time Factors Tissue Inhibitor of Metalloproteinase-1--drug effects Tumor Cells, Cultured