TY - GEN AU - Tie,Jian-Ke AU - Zheng,Mei-Yan AU - Hsiao,Kuang-Ling N AU - Perera,Lalith AU - Stafford,Darrel W AU - Straight,David L TI - Transmembrane domain interactions and residue proline 378 are essential for proper structure, especially disulfide bond formation, in the human vitamin K-dependent gamma-glutamyl carboxylase SN - 1520-4995 PY - 2008///0710 KW - Amino Acid Sequence KW - Amino Acid Substitution KW - genetics KW - Carbon-Carbon Ligases KW - chemistry KW - Cell Membrane KW - enzymology KW - Disulfides KW - Humans KW - Models, Molecular KW - Molecular Sequence Data KW - Peptide Fragments KW - Proline KW - Protein Structure, Tertiary KW - Recombinant Proteins KW - Sequence Homology, Amino Acid KW - Structure-Activity Relationship KW - Vitamin K N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.1021/bi800235r ER -