TY - GEN AU - Sancak,Yasemin AU - Peterson,Timothy R AU - Shaul,Yoav D AU - Lindquist,Robert A AU - Thoreen,Carson C AU - Bar-Peled,Liron AU - Sabatini,David M TI - The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 SN - 1095-9203 PY - 2008///0630 KW - Adaptor Proteins, Signal Transducing KW - Amino Acids KW - metabolism KW - Cell Line KW - Cell Nucleus KW - Cytoplasm KW - Dimerization KW - Guanosine Triphosphate KW - Humans KW - Insulin KW - Leucine KW - Mechanistic Target of Rapamycin Complex 1 KW - Monomeric GTP-Binding Proteins KW - genetics KW - Multiprotein Complexes KW - Mutant Proteins KW - Mutation KW - Neuropeptides KW - Phosphorylation KW - Protein Binding KW - Protein Kinases KW - Proteins KW - Ras Homolog Enriched in Brain Protein KW - Regulatory-Associated Protein of mTOR KW - Signal Transduction KW - TOR Serine-Threonine Kinases KW - Transcription Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1126/science.1157535 ER -