Meikle, Lynsey <br/><br/>
Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.  [electronic resource] 

 -  The Journal of neuroscience : the official journal of the Society for Neuroscience  May 2008 
 - 5422-32 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1529-2401 
<br/><br/><label>Standard No.: </label>10.1523/JNEUROSCI.0955-08.2008  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Age Factors<br/>Animals<br/>Animals, Newborn<br/>Brain--drug effects<br/>Cell Size--drug effects<br/>Dendrites--drug effects<br/>Disease Models, Animal<br/>Everolimus<br/>Immunosuppressive Agents--therapeutic use<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Transgenic<br/>Mutation--genetics<br/>Neurons--drug effects<br/>Oncogene Protein v-akt--metabolism<br/>Signal Transduction--drug effects<br/>Sirolimus--analogs & derivatives<br/>Time Factors<br/>Transcription Factors--metabolism<br/>Tuberous Sclerosis--drug therapy<br/>Tuberous Sclerosis Complex 1 Protein<br/>Tumor Suppressor Proteins--genetics