Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS. [electronic resource]
- Molecular nutrition & food research Sep 2008
- 1082-91 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1613-4133
10.1002/mnfr.200700333 doi
Animals Cell Line Curcuma--chemistry Curcumin--analogs & derivatives DNA-Binding Proteins--drug effects Drug Stability I-kappa B Kinase--drug effects Lipopolysaccharides--pharmacology Macrophage Activation--drug effects Macrophages--drug effects Mice NF-kappa B--metabolism Nitric Oxide--biosynthesis Nitric Oxide Synthase Type II--drug effects Plant Roots--chemistry