Pae, Hyun-Ock

Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS. [electronic resource] - Molecular nutrition & food research Sep 2008 - 1082-91 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1613-4133

10.1002/mnfr.200700333 doi


Animals
Cell Line
Curcuma--chemistry
Curcumin--analogs & derivatives
DNA-Binding Proteins--drug effects
Drug Stability
I-kappa B Kinase--drug effects
Lipopolysaccharides--pharmacology
Macrophage Activation--drug effects
Macrophages--drug effects
Mice
NF-kappa B--metabolism
Nitric Oxide--biosynthesis
Nitric Oxide Synthase Type II--drug effects
Plant Roots--chemistry