Ortiz-Ferrón, Gustavo <br/><br/>
Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism.  [electronic resource] 

 -  Cell research  Jun 2008 
 - 664-76 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1748-7838 
<br/><br/><label>Standard No.: </label>10.1038/cr.2008.54  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Breast Neoplasms--drug therapy<br/>CASP8 and FADD-Like Apoptosis Regulating Protein--genetics<br/>Caspases--metabolism<br/>Cell Line, Tumor<br/>Cell Membrane--drug effects<br/>Death Domain Receptor Signaling Adaptor Proteins--metabolism<br/>Down-Regulation--drug effects<br/>Drug Screening Assays, Antitumor<br/>E2F1 Transcription Factor--metabolism<br/>Enzyme Activation--drug effects<br/>Fas-Associated Death Domain Protein--metabolism<br/>Female<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Membrane Microdomains--drug effects<br/>Myeloid Cell Leukemia Sequence 1 Protein<br/>Protein Isoforms--genetics<br/>Proto-Oncogene Proteins c-bcl-2--genetics<br/>Purines--pharmacology<br/>RNA, Messenger--genetics<br/>RNA, Small Interfering--metabolism<br/>Receptors, TNF-Related Apoptosis-Inducing Ligand--metabolism<br/>Roscovitine<br/>TNF-Related Apoptosis-Inducing Ligand--pharmacology