Lippa, Blaise <br/><br/>
Synthesis and structure based optimization of novel Akt inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Jun 2008 
 - 3359-63 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2008.04.034  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Combinatorial Chemistry Techniques<br/>Crystallography, X-Ray<br/>Disease Models, Animal<br/>Drug Design<br/>Inhibitory Concentration 50<br/>Mice<br/>Molecular Conformation<br/>Molecular Structure<br/>Proto-Oncogene Proteins c-akt--antagonists & inhibitors<br/>Pyrimidines--chemical synthesis<br/>Pyrroles--chemical synthesis<br/>Spiro Compounds--chemical synthesis<br/>Structure-Activity Relationship