TY - GEN AU - Du,Xin AU - She,Ellen AU - Gelbart,Terri AU - Truksa,Jaroslav AU - Lee,Pauline AU - Xia,Yu AU - Khovananth,Kevin AU - Mudd,Suzanne AU - Mann,Navjiwan AU - Moresco,Eva Marie Y AU - Beutler,Ernest AU - Beutler,Bruce TI - The serine protease TMPRSS6 is required to sense iron deficiency SN - 1095-9203 PY - 2008///0602 KW - Anemia, Macrocytic KW - genetics KW - Animals KW - Antimicrobial Cationic Peptides KW - Cell Line, Tumor KW - Gene Expression Regulation KW - Hepcidins KW - Humans KW - Iron KW - blood KW - Iron Deficiencies KW - Membrane Proteins KW - chemistry KW - Mice KW - Mice, Mutant Strains KW - Mice, Transgenic KW - Models, Biological KW - Mutation KW - Phenotype KW - Promoter Regions, Genetic KW - Protein Structure, Tertiary KW - Serine Endopeptidases KW - Signal Transduction KW - Transfection N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1157121 ER -