TY - GEN AU - McDermott,Ultan AU - Iafrate,A John AU - Gray,Nathanael S AU - Shioda,Toshi AU - Classon,Marie AU - Maheswaran,Shyamala AU - Zhou,Wenjun AU - Choi,Hwan Geun AU - Smith,Shannon L AU - Dowell,Lori AU - Ulkus,Lindsey E AU - Kuhlmann,Georgiana AU - Greninger,Patricia AU - Christensen,James G AU - Haber,Daniel A AU - Settleman,Jeffrey TI - Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors SN - 1538-7445 PY - 2008///0610 KW - Anaplastic Lymphoma Kinase KW - Antineoplastic Agents KW - therapeutic use KW - Benzimidazoles KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Line, Tumor KW - Cytogenetic Analysis KW - Drug Evaluation, Preclinical KW - Gene Amplification KW - physiology KW - Genomic Instability KW - drug effects KW - Humans KW - Lung Neoplasms KW - classification KW - Lymphoma KW - Mutation KW - Neuroblastoma KW - Protein Kinase Inhibitors KW - Protein-Tyrosine Kinases KW - antagonists & inhibitors KW - Pyridones KW - Pyrimidines KW - Receptor Protein-Tyrosine Kinases KW - Translocation, Genetic N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-07-6186 ER -