TY  - GEN
AU  - Maguire,Maria
AU  - Nield,Paul C
AU  - Devling,Timothy
AU  - Jenkins,Rosalind E
AU  - Park,B Kevin
AU  - Polański,Radoslaw
AU  - Vlatković,Nikolina
AU  - Boyd,Mark T
TI  - MDM2 regulates dihydrofolate reductase activity through monoubiquitination
SN  - 1538-7445
PY  - 2008///0610
KW  - Cells, Cultured
KW  - Down-Regulation
KW  - Enzyme Activation
KW  - Folic Acid Antagonists
KW  - pharmacology
KW  - Humans
KW  - Methotrexate
KW  - Protein Binding
KW  - Proto-Oncogene Proteins c-mdm2
KW  - chemistry
KW  - RING Finger Domains
KW  - physiology
KW  - Tetrahydrofolate Dehydrogenase
KW  - metabolism
KW  - Ubiquitination
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/0008-5472.CAN-07-5271
ER  -