TY  - GEN
AU  - van Driel,Lydi M J W
AU  - Smedts,Huberdina P M
AU  - Helbing,Willem A
AU  - Isaacs,Aaron
AU  - Lindemans,Jan
AU  - Uitterlinden,André G
AU  - van Duijn,Cornelia M
AU  - de Vries,Jeanne H M
AU  - Steegers,Eric A P
AU  - Steegers-Theunissen,Régine P M
TI  - Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide
SN  - 1522-9645
PY  - 2008///1105
KW  - Adult
KW  - Child
KW  - Drug-Related Side Effects and Adverse Reactions
KW  - Epidemiologic Methods
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Genotype
KW  - Heart Defects, Congenital
KW  - enzymology
KW  - Humans
KW  - Hyperhomocysteinemia
KW  - genetics
KW  - Male
KW  - Niacinamide
KW  - administration & dosage
KW  - Nicotinamide N-Methyltransferase
KW  - Polymorphism, Single Nucleotide
KW  - Pregnancy
KW  - Prenatal Exposure Delayed Effects
KW  - Vitamin B Complex
N1  - Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1093/eurheartj/ehn170
ER  -