TY  - GEN
AU  - Wolin,Ronald L
AU  - Bembenek,Scott D
AU  - Wei,Jianmei
AU  - Crawford,Shelby
AU  - Lundeen,Katherine
AU  - Brunmark,Anders
AU  - Karlsson,Lars
AU  - Edwards,James P
AU  - Blevitt,Jonathan M
TI  - Dual binding site inhibitors of B-RAF kinase
SN  - 1464-3405
PY  - 2008///0715
KW  - Adenosine Triphosphate
KW  - metabolism
KW  - Allosteric Site
KW  - Computer-Aided Design
KW  - Crystallography, X-Ray
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - antagonists & inhibitors
KW  - Hydrocarbons, Aromatic
KW  - chemical synthesis
KW  - Imidazoles
KW  - Inhibitory Concentration 50
KW  - Phosphorylation
KW  - drug effects
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins B-raf
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2008.04.002
ER  -