TY - GEN AU - Numa,Natsuko AU - Ishida,Yoko AU - Nasu,Makiko AU - Sohda,Miwa AU - Misumi,Yoshio AU - Noda,Tadashi AU - Oda,Kimimitsu TI - Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406. Structural importance of the crown domain SN - 1742-464X PY - 2008///0715 KW - Alanine KW - chemistry KW - Alkaline Phosphatase KW - Animals KW - CHO Cells KW - COS Cells KW - Chlorocebus aethiops KW - Cricetinae KW - Cricetulus KW - Humans KW - Hypophosphatasia KW - metabolism KW - Kinetics KW - Protein Conformation KW - Protein Folding KW - Protein Structure, Tertiary KW - Valine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1742-4658.2008.06414.x ER -