Zhou, C

Discovery and biological characterization of a novel series of androgen receptor modulators. [electronic resource] - British journal of pharmacology May 2008 - 440-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1038/bjp.2008.107 doi


Androgen Antagonists--chemistry
Androgen Receptor Antagonists
Anilides--pharmacology
Animals
Antineoplastic Agents, Hormonal--chemistry
Binding, Competitive
Cell Line
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Design
Genes, Reporter
Humans
Male
Mice
Models, Molecular
Molecular Structure
Nitriles--pharmacology
Orchiectomy
Pilot Projects
Prostate--drug effects
Prostatic Neoplasms--drug therapy
Protein Binding
Rats
Rats, Sprague-Dawley
Receptors, Androgen--genetics
Reproducibility of Results
Seminal Vesicles--drug effects
Small Molecule Libraries
Stereoisomerism
Structure-Activity Relationship
Testosterone--metabolism
Tosyl Compounds--pharmacology
Transcriptional Activation--drug effects
Transfection