TY  - GEN
AU  - Leboeuf,Rebecca
AU  - Baumgartner,Jacqueline E
AU  - Benezra,Miriam
AU  - Malaguarnera,Roberta
AU  - Solit,David
AU  - Pratilas,Christine A
AU  - Rosen,Neal
AU  - Knauf,Jeffrey A
AU  - Fagin,James A
TI  - BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines
SN  - 0021-972X
PY  - 2008///0717
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Benzamides
KW  - Benzimidazoles
KW  - Carcinoma
KW  - enzymology
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Diphenylamine
KW  - analogs & derivatives
KW  - Drug Resistance, Neoplasm
KW  - Female
KW  - Humans
KW  - Mice
KW  - Mice, Nude
KW  - Mitogen-Activated Protein Kinase Kinases
KW  - antagonists & inhibitors
KW  - Mutation, Missense
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins B-raf
KW  - genetics
KW  - Substrate Specificity
KW  - Thyroid Neoplasms
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1210/jc.2007-2825
ER  -