TY  - GEN
AU  - Eddine,Ali Nasser
AU  - von Kries,Jens P
AU  - Podust,Mikhail V
AU  - Warrier,Thulasi
AU  - Kaufmann,Stefan H E
AU  - Podust,Larissa M
TI  - X-ray structure of 4,4'-dihydroxybenzophenone mimicking sterol substrate in the active site of sterol 14alpha-demethylase (CYP51)
SN  - 0021-9258
PY  - 2008///0717
KW  - Animals
KW  - Bacterial Proteins
KW  - antagonists & inhibitors
KW  - Benzophenones
KW  - chemistry
KW  - Binding Sites
KW  - drug effects
KW  - Cell Membrane
KW  - metabolism
KW  - Cells, Cultured
KW  - Crystallography, X-Ray
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - Humans
KW  - Macrophages
KW  - Mice
KW  - Models, Molecular
KW  - Mycobacterium tuberculosis
KW  - enzymology
KW  - Mycoses
KW  - drug therapy
KW  - Protein Structure, Tertiary
KW  - Sterols
KW  - biosynthesis
KW  - Structural Homology, Protein
KW  - Tuberculosis
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1074/jbc.M801145200
ER  -