Cunha, T M <br/><br/>
Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice.  [electronic resource] 

 -  British journal of pharmacology  May 2008 
 - 460-70 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0007-1188 
<br/><br/><label>Standard No.: </label>10.1038/bjp.2008.94  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Analgesics--pharmacology<br/>Animals<br/>Arthritis, Experimental--complications<br/>Benzeneacetamides--pharmacology<br/>Cells, Cultured<br/>Chemokine CXCL1--metabolism<br/>Chemotaxis, Leukocyte--drug effects<br/>Cyclooxygenase Inhibitors--pharmacology<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Hyperalgesia--etiology<br/>Indomethacin--pharmacology<br/>Inflammation--complications<br/>Interleukin-8--metabolism<br/>Male<br/>Mesylates--pharmacology<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Inbred DBA<br/>Mice, Knockout<br/>Neutrophil Infiltration--drug effects<br/>Neutrophils--drug effects<br/>Pain Measurement<br/>Receptors, Interleukin-8A--antagonists & inhibitors<br/>Receptors, Interleukin-8B--antagonists & inhibitors<br/>Receptors, Tumor Necrosis Factor, Type I--genetics<br/>Transfection