TY - GEN AU - Kool,Mirjam AU - SoulliƩ,Thomas AU - van Nimwegen,Menno AU - Willart,Monique A M AU - Muskens,Femke AU - Jung,Steffen AU - Hoogsteden,Henk C AU - Hammad,Hamida AU - Lambrecht,Bart N TI - Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells SN - 1540-9538 PY - 2008///0501 KW - Adjuvants, Immunologic KW - administration & dosage KW - Alum Compounds KW - Animals KW - Antibody Formation KW - drug effects KW - Antigen Presentation KW - Antigens KW - CD11c Antigen KW - immunology KW - Cell Movement KW - Cross-Priming KW - Dendritic Cells KW - Immunity KW - Immunity, Innate KW - Inflammation KW - Injections, Intramuscular KW - Injections, Intraperitoneal KW - Lymph Nodes KW - cytology KW - Mice KW - Monocytes KW - Myeloid Differentiation Factor 88 KW - Ovalbumin KW - Signal Transduction KW - Uric Acid KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1084/jem.20071087 ER -