TY - GEN AU - Adams,John W AU - Ramirez,Juan AU - Ortuno,Danny AU - Shi,Yunqing AU - Thomsen,William AU - Richman,Jeremy G AU - Morgan,Michael AU - Dosa,Peter AU - Teegarden,Bradley R AU - Al-Shamma,Hussien AU - Behan,Dominic P AU - Connolly,Daniel T TI - Anti-thrombotic and vascular effects of AR246686, a novel 5-HT2A receptor antagonist SN - 0014-2999 PY - 2008///0902 KW - Amphetamines KW - metabolism KW - Animals KW - Aorta, Thoracic KW - drug effects KW - Bleeding Time KW - Blood Platelets KW - Blood Vessels KW - Cell Membrane KW - DNA KW - biosynthesis KW - Fibrinolytic Agents KW - pharmacokinetics KW - Humans KW - Inositol Phosphates KW - Male KW - Muscle, Smooth, Vascular KW - Phenylurea Compounds KW - pharmacology KW - Platelet Aggregation KW - Protein Binding KW - Rats KW - Rats, Sprague-Dawley KW - Receptor, Serotonin, 5-HT2A KW - Recombinant Proteins KW - chemistry KW - Serotonin KW - Serotonin Antagonists KW - Vasoconstriction N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ejphar.2007.11.056 ER -