Antimyeloma effects of a sesquiterpene lactone parthenolide. [electronic resource]
- Clinical cancer research : an official journal of the American Association for Cancer Research Mar 2008
- 1814-22 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1078-0432
10.1158/1078-0432.CCR-07-1359 doi
Antineoplastic Agents--therapeutic use Apoptosis--drug effects Bone Marrow Cells--drug effects Cell Line, Tumor Cell Proliferation--drug effects Coculture Techniques Dose-Response Relationship, Drug Drug Evaluation, Preclinical Drug Resistance, Neoplasm--drug effects Humans Insulin-Like Growth Factor I--pharmacology Interleukin-6--metabolism Lactones--therapeutic use Leukocytes--drug effects Multiple Myeloma--drug therapy NF-kappa B--metabolism Sesquiterpenes--therapeutic use Tumor Necrosis Factor-alpha--pharmacology