TY - GEN AU - Nezis,Ioannis P AU - Simonsen,Anne AU - Sagona,Antonia P AU - Finley,Kim AU - Gaumer,Sébastien AU - Contamine,Didier AU - Rusten,Tor Erik AU - Stenmark,Harald AU - Brech,Andreas TI - Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain SN - 1540-8140 PY - 2008///0429 KW - Adaptor Proteins, Signal Transducing KW - chemistry KW - Aging KW - metabolism KW - Animals KW - Autophagy KW - genetics KW - Brain KW - cytology KW - DNA-Binding Proteins KW - Drosophila Proteins KW - Drosophila melanogaster KW - Humans KW - Inclusion Bodies KW - Mutation KW - Nerve Tissue Proteins KW - Neurodegenerative Diseases KW - Nuclear Proteins KW - Proteasome Endopeptidase Complex KW - Protein Structure, Tertiary KW - Sequestosome-1 Protein KW - Ubiquitin KW - Ubiquitination N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1083/jcb.200711108 ER -