TY  - GEN
AU  - Steelman,L S
AU  - Navolanic,P M
AU  - Sokolosky,M L
AU  - Taylor,J R
AU  - Lehmann,B D
AU  - Chappell,W H
AU  - Abrams,S L
AU  - Wong,E W T
AU  - Stadelman,K M
AU  - Terrian,D M
AU  - Leslie,N R
AU  - Martelli,A M
AU  - Stivala,F
AU  - Libra,M
AU  - Franklin,R A
AU  - McCubrey,J A
TI  - Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors
SN  - 1476-5594
PY  - 2008///0807
KW  - Amino Acid Substitution
KW  - Antibiotics, Antineoplastic
KW  - agonists
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Doxorubicin
KW  - Drug Resistance, Neoplasm
KW  - drug effects
KW  - Drug Synergism
KW  - Female
KW  - Gene Expression
KW  - Humans
KW  - Mutation, Missense
KW  - PTEN Phosphohydrolase
KW  - antagonists & inhibitors
KW  - Protein Kinases
KW  - genetics
KW  - Proto-Oncogene Proteins c-akt
KW  - Ribosomal Protein S6 Kinases, 70-kDa
KW  - Signal Transduction
KW  - Sirolimus
KW  - TOR Serine-Threonine Kinases
KW  - Transfection
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/onc.2008.49
ER  -