Melo, Fábio R <br/><br/>
An algal sulfated galactan has an unusual dual effect on venous thrombosis due to activation of factor XII and inhibition of the coagulation proteases.  [electronic resource] 

 -  Thrombosis and haemostasis  Mar 2008 
 - 531-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0340-6245 
<br/><br/><label>Standard No.: </label>10.1160/TH07-10-0649  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anticoagulants--adverse effects<br/>Antithrombins--metabolism<br/>Bleeding Time<br/>Blood Coagulation--drug effects<br/>Blood Coagulation Tests<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Factor XIIa--metabolism<br/>Factor Xa--metabolism<br/>Factor Xa Inhibitors<br/>Female<br/>Fibrinolytic Agents--adverse effects<br/>Galactans--adverse effects<br/>Hemorrhage--chemically induced<br/>Heparin--pharmacology<br/>Heparin Cofactor II--metabolism<br/>Humans<br/>Male<br/>Molecular Weight<br/>Protease Inhibitors--pharmacology<br/>Rats<br/>Rats, Wistar<br/>Rhodophyta--chemistry<br/>Sulfates--adverse effects<br/>Thrombin--antagonists & inhibitors<br/>Thrombosis--blood<br/>Venous Thrombosis--blood