TY - GEN AU - Huang,Jing AU - Gan,Qini AU - Han,Limin AU - Li,Jian AU - Zhang,Hai AU - Sun,Ying AU - Zhang,Zongyu AU - Tong,Tanjun TI - SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts SN - 1932-6203 PY - 2008///0626 KW - Antibiotics, Antineoplastic KW - pharmacology KW - Blotting, Western KW - Cell Cycle KW - physiology KW - Cell Proliferation KW - Cells, Cultured KW - Cellular Senescence KW - Cyclin-Dependent Kinase Inhibitor p16 KW - metabolism KW - Diploidy KW - Extracellular Signal-Regulated MAP Kinases KW - Fibroblasts KW - Humans KW - Phosphorylation KW - Retinoblastoma Protein KW - Ribosomal Protein S6 Kinases KW - Signal Transduction KW - Sirolimus KW - Sirtuin 1 KW - Sirtuins KW - antagonists & inhibitors KW - beta-Galactosidase N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0001710 ER -