Huang, Jing

SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. [electronic resource] - PloS one Mar 2008 - e1710 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0001710 doi


Antibiotics, Antineoplastic--pharmacology
Blotting, Western
Cell Cycle--physiology
Cell Proliferation
Cells, Cultured
Cellular Senescence--physiology
Cyclin-Dependent Kinase Inhibitor p16--metabolism
Diploidy
Extracellular Signal-Regulated MAP Kinases--metabolism
Fibroblasts--metabolism
Humans
Phosphorylation
Retinoblastoma Protein--metabolism
Ribosomal Protein S6 Kinases--metabolism
Signal Transduction
Sirolimus--pharmacology
Sirtuin 1
Sirtuins--antagonists & inhibitors
beta-Galactosidase--metabolism