DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice. [electronic resource]
- Nature genetics Apr 2008
- 392-4 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1546-1718
10.1038/ng.95 doi
Aging, Premature--genetics Animals Base Sequence Catalase--genetics DNA Polymerase gamma DNA Repair DNA, Mitochondrial--genetics DNA-Directed DNA Polymerase--genetics Electron Transport Complex IV--genetics Mice Mice, Knockout Mice, Transgenic Molecular Sequence Data Mutagenesis Oxidative Stress Phenotype Point Mutation--genetics Sequence Deletion Sequence Homology, Nucleic Acid Tissue Distribution