TY  - GEN
AU  - Benod,Cindy
AU  - Subra,Guy
AU  - Nahoum,Virginie
AU  - Mallavialle,Aude
AU  - Guichou,Jean-François
AU  - Milhau,Julien
AU  - Roblés,Samuel
AU  - Bourguet,William
AU  - Pascussi,Jean-Marc
AU  - Balaguer,Patrick
AU  - Chavanieu,Alain
TI  - N-1H-benzimidazol-5-ylbenzenesulfonamide derivatives as potent hPXR agonists
SN  - 1464-3391
PY  - 2008///0515
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Benzimidazoles
KW  - chemical synthesis
KW  - Cell Line
KW  - Cytochrome P-450 CYP2B6
KW  - Cytochrome P-450 CYP3A
KW  - Gene Expression Regulation
KW  - drug effects
KW  - Humans
KW  - Models, Molecular
KW  - Molecular Structure
KW  - Oxidoreductases, N-Demethylating
KW  - Pregnane X Receptor
KW  - RNA, Messenger
KW  - Receptors, Steroid
KW  - agonists
KW  - Structure-Activity Relationship
KW  - Sulfonamides
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmc.2008.02.020
ER  -