Serreze, David V

Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Mar 2008 - 3250-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0022-1767

10.4049/jimmunol.180.5.3250 doi


Animals
CD8-Positive T-Lymphocytes--immunology
Cell Differentiation--genetics
Chromosome Mapping
Clonal Deletion--genetics
Clone Cells
Diabetes Mellitus, Type 1--genetics
Genetic Markers
Genetic Predisposition to Disease
Mice
Mice, Congenic
Mice, Inbred C57BL
Mice, Inbred NOD
Mice, Transgenic
Quantitative Trait Loci--immunology
Receptors, Antigen, T-Cell, alpha-beta--biosynthesis
Thymus Gland--immunology