TY - GEN AU - Chen,Yuhpyng L AU - Obach,R Scott AU - Braselton,John AU - Corman,Michael L AU - Forman,James AU - Freeman,Jody AU - Gallaschun,Randall J AU - Mansbach,Robert AU - Schmidt,Anne W AU - Sprouse,Jeffrey S AU - Tingley Iii,F David AU - Winston,Elizabeth AU - Schulz,David W TI - 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists SN - 0022-2623 PY - 2008///0605 KW - Action Potentials KW - drug effects KW - Administration, Oral KW - Adrenocorticotropic Hormone KW - blood KW - Aminopyridines KW - chemical synthesis KW - Animals KW - Antidepressive Agents KW - Cerebral Cortex KW - metabolism KW - Corticotropin-Releasing Hormone KW - pharmacology KW - Dogs KW - Fasting KW - Humans KW - Injections, Intravenous KW - Locus Coeruleus KW - physiology KW - Male KW - Pituitary Gland KW - Postprandial Period KW - Radioligand Assay KW - Rats KW - Rats, Sprague-Dawley KW - Receptors, Corticotropin-Releasing Hormone KW - antagonists & inhibitors KW - Reflex, Startle KW - Structure-Activity Relationship KW - CRF Receptor, Type 1 N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm070579c ER -