Chen, Yuhpyng L <br/><br/>
2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists.  [electronic resource] 

 -  Journal of medicinal chemistry  Mar 2008 
 - 1385-92 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm070579c  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Action Potentials--drug effects<br/>Administration, Oral<br/>Adrenocorticotropic Hormone--blood<br/>Aminopyridines--chemical synthesis<br/>Animals<br/>Antidepressive Agents--chemical synthesis<br/>Cerebral Cortex--metabolism<br/>Corticotropin-Releasing Hormone--pharmacology<br/>Dogs<br/>Fasting<br/>Humans<br/>Injections, Intravenous<br/>Locus Coeruleus--physiology<br/>Male<br/>Pituitary Gland--metabolism<br/>Postprandial Period<br/>Radioligand Assay<br/>Rats<br/>Rats, Sprague-Dawley<br/>Receptors, Corticotropin-Releasing Hormone--antagonists & inhibitors<br/>Reflex, Startle--drug effects<br/>Structure-Activity Relationship<br/>CRF Receptor, Type 1