Wu, Shu

High tidal volume ventilation activates Smad2 and upregulates expression of connective tissue growth factor in newborn rat lung. [electronic resource] - Pediatric research Mar 2008 - 245-50 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0031-3998

10.1203/PDR.0b013e318163a8cc doi


Animals
Animals, Newborn
Connective Tissue Growth Factor
Immediate-Early Proteins--genetics
Intercellular Signaling Peptides and Proteins--genetics
Interleukin-6--genetics
Lung--growth & development
Lung Diseases--etiology
Phosphorylation
Positive-Pressure Respiration--adverse effects
RNA, Messenger--metabolism
Rats
Rats, Sprague-Dawley
Signal Transduction
Smad2 Protein--metabolism
Smad7 Protein--metabolism
Tidal Volume
Time Factors
Transforming Growth Factor beta--metabolism
Tumor Necrosis Factor-alpha
Up-Regulation