Schmidt, C J

Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia. [electronic resource] - The Journal of pharmacology and experimental therapeutics May 2008 - 681-90 p. digital

Publication Type: Journal Article

1521-0103

10.1124/jpet.107.132910 doi


Animals
Behavior, Animal--drug effects
Brain--drug effects
Cyclic AMP--metabolism
Cyclic GMP--metabolism
Dopamine--metabolism
Male
Mice
Mice, Inbred C57BL
Motor Activity--drug effects
Phosphodiesterase Inhibitors--blood
Phosphoric Diester Hydrolases--genetics
Pyrazoles--pharmacology
Quinolines--pharmacology
Rats
Rats, Inbred F344
Recombinant Proteins--antagonists & inhibitors
Reflex, Startle--drug effects
Schizophrenia--drug therapy