Schmidt, C J Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia. [electronic resource] - The Journal of pharmacology and experimental therapeutics May 2008 - 681-90 p. digital Publication Type: Journal Article ISSN: 1521-0103 Standard No.: 10.1124/jpet.107.132910 doi Subjects--Topical Terms: AnimalsBehavior, Animal--drug effectsBrain--drug effectsCyclic AMP--metabolismCyclic GMP--metabolismDopamine--metabolismMaleMiceMice, Inbred C57BLMotor Activity--drug effectsPhosphodiesterase Inhibitors--bloodPhosphoric Diester Hydrolases--geneticsPyrazoles--pharmacologyQuinolines--pharmacologyRatsRats, Inbred F344Recombinant Proteins--antagonists & inhibitorsReflex, Startle--drug effectsSchizophrenia--drug therapy