Zhao, Hai-Tao

Unusual binding mode of the 2S4R stereoisomer of the potent aldose reductase cyclic imide inhibitor fidarestat (2S4S) in the 15 K crystal structure of the ternary complex refined at 0.78 A resolution: implications for the inhibition mechanism. [electronic resource] - Journal of medicinal chemistry Mar 2008 - 1478-81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0022-2623

10.1021/jm701514k doi


Aldehyde Reductase--antagonists & inhibitors
Crystallography, X-Ray
Humans
Imidazolidines--chemistry
Models, Molecular
Molecular Structure
Protein Binding
Stereoisomerism