Vinogradova, Tatiana M <br/><br/>
Constitutive phosphodiesterase activity restricts spontaneous beating rate of cardiac pacemaker cells by suppressing local Ca2+ releases.  [electronic resource] 

 -  Circulation research  Apr 2008 
 - 761-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Intramural 
<br/><br/><label>ISSN: </label>1524-4571 
<br/><br/><label>Standard No.: </label>10.1161/CIRCRESAHA.107.161679  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>1-Methyl-3-isobutylxanthine--pharmacology<br/>Animals<br/>Biological Clocks--physiology<br/>Calcium--metabolism<br/>Calcium-Binding Proteins--metabolism<br/>Cyclic AMP--metabolism<br/>Cyclic AMP-Dependent Protein Kinases--metabolism<br/>Enzyme Activation<br/>Heart Rate--physiology<br/>Patch-Clamp Techniques<br/>Phosphodiesterase Inhibitors--pharmacology<br/>Phosphoric Diester Hydrolases--drug effects<br/>Phosphorylation<br/>Rabbits<br/>Ryanodine Receptor Calcium Release Channel--metabolism<br/>Signal Transduction--physiology<br/>Sinoatrial Node--metabolism