Emoto, C Non-invasive method to detect induction of CYP3A4 in chimeric mice with a humanized liver. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems Mar 2008 - 239-48 p. digital Publication Type: Journal Article ISSN: 0049-8254 Standard No.: 10.1080/00498250701760159 doi Subjects--Topical Terms: AnimalsBiological Assay--methodsChimera--metabolismChromatographyCytochrome P-450 CYP3A--biosynthesisDexamethasone--administration & dosageEnzyme Induction--drug effectsHumansImmunohistochemistryKineticsLiver--drug effectsMiceMicrosomes, Liver--drug effectsRecombinant Proteins--metabolismRifampin--pharmacologySubstrate Specificity--drug effects