Hughes, David T <br/><br/>
The synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells.  [electronic resource] 

 -  Cancer investigation  Mar 2008 
 - 118-27 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1532-4192 
<br/><br/><label>Standard No.: </label>10.1080/07357900701522612  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adipocytes--cytology<br/>Apoptosis--drug effects<br/>Blotting, Western<br/>Cell Proliferation--drug effects<br/>Cerulenin--pharmacology<br/>Drug Synergism<br/>Drug Therapy, Combination<br/>Fatty Acid Synthases--antagonists & inhibitors<br/>Fatty Acid Synthesis Inhibitors--pharmacology<br/>Glycerolphosphate Dehydrogenase--metabolism<br/>Humans<br/>Imidazoles--pharmacology<br/>Liposarcoma--drug therapy<br/>Oleanolic Acid--analogs & derivatives<br/>Palmitic Acid--metabolism<br/>Tumor Cells, Cultured--drug effects<br/>fas Receptor--genetics