TY - GEN AU - Ninichuk,Volha AU - Clauss,Sebastian AU - Kulkarni,Onkar AU - Schmid,Holger AU - Segerer,Stephan AU - Radomska,Ewa AU - Eulberg,Dirk AU - Buchner,Klaus AU - Selve,Norma AU - Klussmann,Sven AU - Anders,Hans-Joachim TI - Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice SN - 0002-9440 PY - 2008///0509 KW - Animals KW - Aptamers, Nucleotide KW - therapeutic use KW - Cell Count KW - Cell Movement KW - drug effects KW - Cell Proliferation KW - Cells, Cultured KW - Chemokine CCL2 KW - antagonists & inhibitors KW - Diabetes Mellitus, Type 1 KW - complications KW - Diabetic Nephropathies KW - prevention & control KW - Glomerular Filtration Rate KW - Kidney KW - Macrophages KW - Male KW - Mice KW - Mice, Inbred NOD KW - Nephrectomy KW - Nephritis, Interstitial KW - etiology KW - RNA, Messenger KW - metabolism KW - Receptors, CCR2 KW - Time Factors KW - Transforming Growth Factor beta N1 - Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2353/ajpath.2008.070601 ER -