Ninichuk, Volha <br/><br/>
Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice.  [electronic resource] 

 -  The American journal of pathology  Mar 2008 
 - 628-37 p.  digital 
<br/><br/> Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0002-9440 
<br/><br/><label>Standard No.: </label>10.2353/ajpath.2008.070601  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aptamers, Nucleotide--therapeutic use<br/>Cell Count<br/>Cell Movement--drug effects<br/>Cell Proliferation--drug effects<br/>Cells, Cultured<br/>Chemokine CCL2--antagonists & inhibitors<br/>Diabetes Mellitus, Type 1--complications<br/>Diabetic Nephropathies--prevention & control<br/>Glomerular Filtration Rate--drug effects<br/>Kidney--drug effects<br/>Macrophages--drug effects<br/>Male<br/>Mice<br/>Mice, Inbred NOD<br/>Nephrectomy<br/>Nephritis, Interstitial--etiology<br/>RNA, Messenger--metabolism<br/>Receptors, CCR2--metabolism<br/>Time Factors<br/>Transforming Growth Factor beta--metabolism