TY - GEN AU - Ott,Gregory R AU - Asakawa,Naoyuki AU - Lu,Zhonghui AU - Anand,Rajan AU - Liu,Rui-Qin AU - Covington,Maryanne B AU - Vaddi,Krishna AU - Qian,Mingxin AU - Newton,Robert C AU - Christ,David D AU - Trzaskos,James M AU - Duan,James J-W TI - Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents SN - 1464-3405 PY - 2008///0519 KW - ADAM Proteins KW - antagonists & inhibitors KW - ADAM17 Protein KW - Animals KW - Area Under Curve KW - Benzamides KW - blood KW - Biological Availability KW - Dogs KW - Half-Life KW - Molecular Structure KW - Rats KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2008.01.075 ER -