TY  - GEN
AU  - Zhou,Yuefen
AU  - Li,Lian-Sheng
AU  - Dragovich,Peter S
AU  - Murphy,Douglas E
AU  - Tran,Chinh V
AU  - Ruebsam,Frank
AU  - Webber,Stephen E
AU  - Shah,Amit M
AU  - Tsan,Mei
AU  - Averill,April
AU  - Showalter,Richard E
AU  - Patel,Rupal
AU  - Han,Qing
AU  - Zhao,Qiang
AU  - Hermann,Thomas
AU  - Kissinger,Charles R
AU  - Lebrun,Laurie
AU  - Sergeeva,Maria V
TI  - Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents
SN  - 1464-3405
PY  - 2008///0512
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Drug Stability
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Microsomes, Liver
KW  - metabolism
KW  - Models, Molecular
KW  - Pyridazines
KW  - RNA-Dependent RNA Polymerase
KW  - antagonists & inhibitors
KW  - Thiadiazines
KW  - Viral Nonstructural Proteins
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2008.01.005
ER  -