TY - GEN AU - Lee,Insuk AU - Lehner,Ben AU - Crombie,Catriona AU - Wong,Wendy AU - Fraser,Andrew G AU - Marcotte,Edward M TI - A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans SN - 1546-1718 PY - 2008///0226 KW - Animals KW - Bayes Theorem KW - Caenorhabditis elegans KW - genetics KW - Computational Biology KW - methods KW - Databases, Genetic KW - Dystrophin-Associated Protein Complex KW - Epidermal Growth Factor KW - metabolism KW - Female KW - Gene Expression Regulation, Developmental KW - Gene Regulatory Networks KW - Genes, Helminth KW - Genes, ras KW - Genetic Linkage KW - Helminth Proteins KW - Likelihood Functions KW - Mitogen-Activated Protein Kinases KW - Models, Biological KW - Models, Genetic KW - Phenotype KW - Predictive Value of Tests KW - Probability KW - Proteome KW - RNA Interference KW - RNA, Helminth KW - RNA, Messenger KW - ROC Curve KW - Repressor Proteins KW - Reproducibility of Results KW - Retinoblastoma Protein KW - antagonists & inhibitors KW - Signal Transduction KW - Vulva KW - growth & development N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ng.2007.70 ER -