TY  - GEN
AU  - Zanna,Claudia
AU  - Ghelli,Anna
AU  - Porcelli,Anna Maria
AU  - Karbowski,Mariusz
AU  - Youle,Richard J
AU  - Schimpf,Simone
AU  - Wissinger,Bernd
AU  - Pinti,Marcello
AU  - Cossarizza,Andrea
AU  - Vidoni,Sara
AU  - Valentino,Maria Lucia
AU  - Rugolo,Michela
AU  - Carelli,Valerio
TI  - OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion
SN  - 1460-2156
PY  - 2008///0423
KW  - Adenosine Triphosphate
KW  - biosynthesis
KW  - Apoptosis
KW  - drug effects
KW  - Cells, Cultured
KW  - DNA Mutational Analysis
KW  - methods
KW  - DNA, Mitochondrial
KW  - analysis
KW  - Electron Transport
KW  - Fibroblasts
KW  - GTP Phosphohydrolases
KW  - genetics
KW  - Gene Deletion
KW  - Humans
KW  - Mitochondria
KW  - metabolism
KW  - Optic Atrophy, Autosomal Dominant
KW  - Oxidants
KW  - pharmacology
KW  - Oxidative Phosphorylation
KW  - Skin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1093/brain/awm335
ER  -