Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release. [electronic resource]
- Cellular signalling Apr 2008
- 625-36 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
0898-6568
10.1016/j.cellsig.2007.11.016 doi
Animals Antigens--metabolism Calcium Signaling Cell Degranulation--drug effects Cell Membrane--enzymology Cells, Cultured Cytokines--metabolism Dinoprostone--metabolism Enzyme Activation Hypersensitivity--enzymology Inositol 1,4,5-Trisphosphate--metabolism Macrophages--drug effects Mice Mice, Inbred C57BL Pertussis Toxin--pharmacology Phosphatidylinositol 3-Kinases--metabolism Phospholipase C beta--metabolism Phospholipase C gamma--metabolism Phosphorylation Protein Kinase C--metabolism Protein Kinase C beta Protein Kinase C-alpha--metabolism Protein Transport Receptor Aggregation Receptor Cross-Talk Receptors, IgE--metabolism Receptors, Prostaglandin E--metabolism Signal Transduction--drug effects Time Factors