TY - GEN AU - Muoio,Deborah M AU - Newgard,Christopher B TI - Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes SN - 1471-0080 PY - 2008///0305 KW - Animals KW - Diabetes Mellitus, Type 2 KW - genetics KW - Glucose KW - metabolism KW - Humans KW - Insulin KW - Insulin Resistance KW - physiology KW - Insulin-Secreting Cells KW - pathology KW - Signal Transduction N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1038/nrm2327 ER -