Selvendiran, Karuppaiyah

NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts. [electronic resource] - Cell cycle (Georgetown, Tex.) Jan 2008 - 81-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural

1551-4005

10.4161/cc.7.1.5103 doi


Animals
Aspirin--analogs & derivatives
Cell Line, Tumor
Cisplatin--pharmacology
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm--drug effects
ErbB Receptors--antagonists & inhibitors
Female
Humans
Mice
Mice, Inbred BALB C
Mice, Nude
Ovarian Neoplasms--drug therapy
Proto-Oncogene Proteins c-bcl-2--biosynthesis
STAT3 Transcription Factor--antagonists & inhibitors
Signal Transduction--drug effects
Transplantation, Heterologous--pathology