TY - GEN AU - Smaill,Jeff B AU - Lee,Ho H AU - Palmer,Brian D AU - Thompson,Andrew M AU - Squire,Christopher J AU - Baker,Edward N AU - Booth,R John AU - Kraker,Alan AU - Hook,Ken AU - Denny,William A TI - Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases SN - 1464-3405 PY - 2008///0324 KW - Carbazoles KW - chemical synthesis KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Checkpoint Kinase 1 KW - Combinatorial Chemistry Techniques KW - Humans KW - Molecular Structure KW - Nuclear Proteins KW - Protein Kinase Inhibitors KW - Protein Kinases KW - metabolism KW - Protein-Tyrosine Kinases KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2007.12.046 ER -