TY - GEN AU - Carter,Bing Z AU - Mak,Duncan H AU - Schober,Wendy D AU - Dietrich,Martin F AU - Pinilla,Clemencia AU - Vassilev,Lyubomir T AU - Reed,John C AU - Andreeff,Michael TI - Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5 SN - 0006-4971 PY - 2008///0515 KW - Aniline Compounds KW - agonists KW - Antineoplastic Agents, Alkylating KW - Apoptosis KW - drug effects KW - Diterpenes KW - Drug Synergism KW - Epoxy Compounds KW - Female KW - Humans KW - Imidazoles KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Male KW - Phenanthrenes KW - Piperazines KW - Proto-Oncogene Proteins c-mdm2 KW - antagonists & inhibitors KW - Receptors, TNF-Related Apoptosis-Inducing Ligand KW - metabolism KW - Signal Transduction KW - TNF-Related Apoptosis-Inducing Ligand KW - Tumor Suppressor Protein p53 KW - U937 Cells KW - X-Linked Inhibitor of Apoptosis Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1182/blood-2007-05-091504 ER -